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T-лимфоциты частично помнят ковид
Jan. 30th, 2023 02:43 pmШироко охватывающий Т-лимфоцитный ответ на ковид в настоящее время является действенным, но распознавание семи из десяти Т-клеточных мишеней, мутировавших в вариантах SARS-CoV-2, нарушено. Исследование было с людьми, болевшими ковидом в начале пандемии. Образцы взяты и исследованы где-то через полгода.
Согласно новому исследованию, мутации снижают эффективность Т-лимфоцитов.
https://www.birmingham.ac.uk/news/2022/immune-t-cell-defence-is-coping-with-covid-19-variants-of-concern-for-now
Broad T-cell response is currently protective but recognition of seven out of ten T-cell targets mutated in SARS-CoV-2 variants is impaired.
Immune T cells are continuing to target the spike protein of SARS-CoV-2 variants of concern, although mutations are making some T cells less effective, according to new research.
Published in Nature Immunology, researchers from the University of Birmingham have shown that human T cell immunity is currently coping with mutations that have accumulated over time in COVID-19 variants.
Согласно новому исследованию, мутации снижают эффективность Т-лимфоцитов.
https://www.birmingham.ac.uk/news/2022/immune-t-cell-defence-is-coping-with-covid-19-variants-of-concern-for-now
Broad T-cell response is currently protective but recognition of seven out of ten T-cell targets mutated in SARS-CoV-2 variants is impaired.
Immune T cells are continuing to target the spike protein of SARS-CoV-2 variants of concern, although mutations are making some T cells less effective, according to new research.
Published in Nature Immunology, researchers from the University of Birmingham have shown that human T cell immunity is currently coping with mutations that have accumulated over time in COVID-19 variants.
In the study, funded by the National Institute for Health and Care Research, the research partner of the NHS, the researchers tested CD4+ T cells collected at the start of the pandemic from healthcare workers infected with COVID-19.
